170 Steelwell Rd. #200
Brampton, ON L6T 5T3
Commercial Properties for Lease in Guelph
Explore commercial properties for lease in Guelph including industrial buildings, office space, retail units, warehouses, mixed-use developments, and commercial leasing opportunities across Southwestern Ontario.
Guelph continues attracting manufacturers, retailers, professional businesses, entrepreneurs, and commercial tenants searching for industrial, office, retail, and mixed-use leasing opportunities throughout the region.
From Downtown Guelph and commercial corridors to industrial parks and expanding business districts, Guelph remains one of Ontario’s growing commercial leasing and investment markets.
Commercial Properties for Lease in Guelph | Commercial Real Estate Guelph
Commercial Properties for Lease in Guelph | Commercial Real Estate Guelph
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85 NORFOLK Street Unit# 202 in Guelph: Office for lease : MLS®# 40845366
85 NORFOLK Street Unit# 202 Guelph N1H 4J4 
$15 /sqftOffice- Status:
- For Lease
- MLS® Num:
- 40845366
- Floor Area:
- 908 sq. ft.
Professional medical office space available in a highly desirable, professionally managed building near downtown Guelph. This large, well-designed office suite features four separate private offices, offering excellent functionality for a variety of medical or professional uses. The space includes a generously sized waiting room, a private bathroom, and a soundproof office setup to ensure privacy and comfort for both staff and clients. Located within close proximity to downtown Guelph, this property offers exceptional convenience for patients and professionals alike. The building is well maintained and home to a strong existing community of medical tenants, creating a reputable and established healthcare environment. An excellent opportunity for practitioners seeking a turnkey space in a prime, accessible location with strong professional surroundings. (id:2493) More detailsListed by Vancor Realty Inc.
- Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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100 - 21 LEWIS ROAD in Guelph (Willow West/Sugarbush/West Acres): Office for lease : MLS®# X13527660
100 - 21 LEWIS ROAD Guelph (Willow West/Sugarbush/West Acres) N1H 1E9
$15.50 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13527660
- Floor Area:
- 3,300 sq. ft.
This professional, freestanding office building offers an exceptional opportunity for a growing or established business. Perfectly situated adjacent to the Hanlon Expressway, the property provides unparalleled exposure and seamless connectivity for clients and employees alike. The site features an extensive, paved parking lot that comfortably accommodates staff and visitors, complemented by easy access to nearby public transit routes. With a high-quality finish and a layout designed for efficiency, this space serves as an ideal headquarters for your professional operations. Furthermore, the strategic location allows for highly effective exterior branding, maximizing visibility to the steady stream of daily commuter traffic. The property is well-maintained with reliable exterior infrastructure, providing a secure and professional environment that is optimized for both private focus and team collaboration, making it a versatile choice for any business looking to establish a strong, accessible presence in the area. (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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85 NORFOLK Street Unit# 303 in Guelph: Office for lease : MLS®# 40845358
85 NORFOLK Street Unit# 303 Guelph N1H 4J4
$15 /sqftOffice- Status:
- For Lease
- MLS® Num:
- 40845358
- Floor Area:
- 911 sq. ft.
Professional medical office space available in a highly desirable, professionally managed building near downtown Guelph. This large, well-designed office suite features four separate private offices, offering excellent functionality for a variety of medical or professional uses. The space includes a generously sized waiting room, a private bathroom, and a soundproof office setup to ensure privacy and comfort for both staff and clients. Located within close proximity to downtown Guelph, this property offers exceptional convenience for patients and professionals alike. The building is well maintained and home to a strong existing community of medical tenants, creating a reputable and established healthcare environment. An excellent opportunity for practitioners seeking a turnkey space in a prime, accessible location with strong professional surroundings. (id:2493) More detailsListed by Vancor Realty Inc. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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85 NORFOLK Street Unit# 201 in Guelph: Office for lease : MLS®# 40845361
85 NORFOLK Street Unit# 201 Guelph N1H 4J4
$15 /sqftOffice- Status:
- For Lease
- MLS® Num:
- 40845361
- Floor Area:
- 1,417 sq. ft.
Professional medical office space available in a highly desirable, professionally managed building near downtown Guelph. This large, well-designed office suite features four separate private offices, offering excellent functionality for a variety of medical or professional uses. The space includes a generously sized waiting room, a private bathroom, and a soundproof office setup to ensure privacy and comfort for both staff and clients. Located within close proximity to downtown Guelph, this property offers exceptional convenience for patients and professionals alike. The building is well maintained and home to a strong existing community of medical tenants, creating a reputable and established healthcare environment. An excellent opportunity for practitioners seeking a turnkey space in a prime, accessible location with strong professional surroundings. (id:2493) More detailsListed by Vancor Realty Inc. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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B3 - 45 WYNDHAM STREET N in Guelph (Downtown): Retail for lease : MLS®# X13523880
B3 - 45 WYNDHAM STREET N Guelph (Downtown) N1H 4E4
$12.50 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13523880
- Floor Area:
- 1,955 sq. ft.
- Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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B1 - 45 WYNDHAM STREET N in Guelph (Downtown): Retail for lease : MLS®# X13523878
B1 - 45 WYNDHAM STREET N Guelph (Downtown) N1H 4E4
$12.50 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13523878
- Floor Area:
- 3,669 sq. ft.
Prime retail space available in a high-visibility location, ideally configured for a gym, fitness studio, or wellness concept. This space offers the open floor plan, ceiling height, and layout flexibility that fitness operators need, allowing for everything from open training areas and equipment floors to group class studios, spin rooms, or functional training zones.The unit benefits from strong exposure and steady traffic, giving your brand the visibility that drives membership growth and walk-in interest. Convenient parking and easy access make it simple for members to build a consistent routine, while the surrounding mix of residential and commercial density provides a built-in customer base within your immediate catchment area.Whether you are launching a boutique studio, expanding an established fitness brand, or bringing a new wellness concept to the area, this space provides the room to grow and the location to attract a loyal membership. With flexible layout potential and a setting designed to support a high-energy, high-traffic business, it is an ideal home for an operator ready to make an impact.Contact Above All Commercial to book a private viewing. (id:2493) More detailsListed by RE/MAX REAL ESTATE CENTRE INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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103 - 45 WYNDHAM STREET N in Guelph (Downtown): Retail for lease : MLS®# X13523828
103 - 45 WYNDHAM STREET N Guelph (Downtown) N1H 4E4
$33 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13523828
- Floor Area:
- 2,873 sq. ft.
Rare turnkey opportunity in the heart of downtown Guelph. This high-end retail/office space includes over $200,000 in premium leasehold improvements from the previous tenant that were never used, leaving it fully move-in ready for the next occupant and eliminating the time and cost of a fresh build-out.A standout feature is that each office is plumbed with its own water supply, making the space ideally suited for a hair salon, dental or medical practice, med spa, wellness studio, or any service business that needs water at multiple stations. Adding that kind of infrastructure typically costs tens of thousands of dollars, and here it is already in place and ready to use.Positioned in Guelph's vibrant downtown core, the space benefits from strong pedestrian traffic, an established mix of retail and professional neighbours, excellent visibility, and convenient nearby parking. Downtown Guelph continues to attract discerning consumers and professionals, making it an ideal setting for a business that wants to make a lasting impression in one of the region's most sought-after commercial districts.This is a rare chance to secure a premium address with significant leasehold value already built in, allowing the right operator to open with major savings and a competitive edge from day one. Whether you are an established business looking to expand or a new venture launching in style, this space offers exceptional value and flexibility. Contact Above All Commercial to book a private viewing. (id:2493) More detailsListed by RE/MAX REAL ESTATE CENTRE INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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200 - 15 LEWIS ROAD in Guelph (Willow West/Sugarbush/West Acres): Office for lease : MLS®# X13521152
200 - 15 LEWIS ROAD Guelph (Willow West/Sugarbush/West Acres) N1H 1E9
$15.50 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13521152
- Floor Area:
- 2,500 sq. ft.
This turnkey second-floor office space offers 2,500 square feet of professional, move-in-ready workspace in the heart of North Guelph. The efficient, built-out layout includes eight spacious private offices, an executive boardroom for client meetings, two private washrooms, and a dedicated kitchenette/lunchroom, making it ideal for medical, wellness, or professional service firms. Situated at the corner of the Hanlon Parkway and Speedvale Avenue, the property provides superior regional connectivity to Highway 7 and the 401, while offering the convenience of on-site parking for both staff and visitors. Join a vibrant, professional community of health and wellness tenants such as The Womb Clinic and Green Aura Clinic, in a location that perfectly balances high visibility with a quiet, functional office setting suitable for clinical practices, administrative headquarters, or consulting services. (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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7 - 595 HANLON CREEK BOULEVARD in Guelph (Kortright Hills): Industrial for lease : MLS®# X13509710
7 - 595 HANLON CREEK BOULEVARD Guelph (Kortright Hills) N1C 0A1
$22 /sqftIndustrial- Status:
- For Lease
- MLS® Num:
- X13509710
- Major Bus.:
- Industrial
- Build. Type:
- Warehouse
- Floor Area:
- 2,356 sq. ft.
Brand New CORNER UNIT!!! GF Warehouse + 2nd-floor office space for lease. Located in South Guelph's most desirable - Hanlon Creek Business Park. 5-minute drive from Highway 401 and close to Toronto, Hamilton, and Kitchener/Waterloo. This Premium Corner Unit facing Downey Road has great signage exposure - Outstanding visibility and abundance of natural light through 3 side glass walls/windows. It is suitable for a wide range of Permitted Uses, including Showroom, Office, Medical Store, Clinic, Training Facility, Commercial School, Laboratory or Research Facility, and Print Shop. This Flexible Commercial & Industrial unit has a drive-in loading bay with 10 ft wide garage door, 22-foot clearance, and A Mezzanine Level. The ground floor offers excellent open space & functionality - ideal for commercial or industrial operations. ** High Ceiling, very well-lit unit, and front and back entrance doors. One of the best units in the plaza ** (id:2493) More detailsListed by NEW AGE REAL ESTATE GROUP INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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78 CARDEN STREET in Guelph (Downtown): Office for lease : MLS®# X13452280
78 CARDEN STREET Guelph (Downtown) N1H 2Z7
$16 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13452280
- Bathrooms:
- 3
- Floor Area:
- 7,500 sq. ft.
This turnkey office space in downtown Guelph provides a highly functional layout featuring an open-concept work area, private offices, a kitchen/staff room, and three washrooms, including one barrier-free accessible unit. The facility is well-equipped for diverse operational requirements, offering three-phase power and a full basement with 7-foot ceilings suitable for workshop use or secure storage. Zoned D.1, the premises support a wide range of permitted uses, including professional and administrative offices, financial institutions, medical clinics, personal service shops, and cultural facilities, making this an ideal hub for large organizations or businesses seeking a versatile, high-capacity commercial environment. **** MAIN LEVEL 4500 sf at $16 , BASEMENT 3000 sf at $8 **** (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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295 SOUTHGATE Drive Unit# 2 in Guelph: Office for lease : MLS®# 40840056
295 SOUTHGATE Drive Unit# 2 Guelph N1G 3M5
$18 /sqftOffice- Status:
- For Lease
- MLS® Num:
- 40840056
- Floor Area:
- 1,485 sq. ft.
Office leasing opportunity at 295 Southgate Drive. Drive up office space with ample parking and lots of natural light. Unit consists of 3 private offices, kitchenette, boardroom, and shop space. Landlord will install new flooring of tenant's choice (from landlord samples). Longer term leases preferred. Rogers Fibre Internet connection available. TMI is only $4.71/sq. ft. Onsite landlord maintains property. (id:2493) More detailsListed by COLDWELL BANKER PETER BENNINGER REALTY - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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A7, A8 - 320 EASTVIEW RD in Guelph (Grange Road): Retail for lease : MLS®# X13425810
A7, A8 - 320 EASTVIEW RD Guelph (Grange Road) N1E 0L2
$24 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13425810
- Floor Area:
- 2,235 sq. ft.
Excellent commercial opportunity in the fast-growing East Guelph area. Approximately 2235 sq. ft. unit featuring high ceilings and ample parking. Previously operated as a restaurant and suitable for a variety of commercial uses including retail, grocery store, restaurant, furniture store and other service-based businesses. Located in a busy plaza with great potential for multiple business concepts! (id:2493) More detailsListed by CENTURY 21 GREEN REALTY INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
Data was last updated July 12, 2026 at 04:45 PM (UTC)
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Guelph Commercial Leasing FAQs
What types of commercial properties are available for lease in Guelph?
Commercial leasing opportunities in Guelph may include industrial buildings, office space, retail units, warehouses, mixed-use developments, and commercial leasing properties across Southwestern Ontario.
Why do businesses lease commercial properties in Guelph?
Guelph attracts commercial tenants due to its growing population, manufacturing sector, transportation access, expanding business market, and strong commercial development across Southwestern Ontario.
Can businesses find industrial, office, and retail leasing opportunities in Guelph?
Commercial tenants can explore industrial space, office leasing opportunities, retail units, warehouses, mixed-use developments, and commercial leasing opportunities throughout Guelph and surrounding regional markets.
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