170 Steelwell Rd. #200
Brampton, ON L6T 5T3
Commercial Properties for Lease in Guelph
Explore commercial properties for lease in Guelph including industrial buildings, office space, retail units, warehouses, mixed-use developments, and commercial leasing opportunities across Southwestern Ontario.
Guelph continues attracting manufacturers, retailers, professional businesses, entrepreneurs, and commercial tenants searching for industrial, office, retail, and mixed-use leasing opportunities throughout the region.
From Downtown Guelph and commercial corridors to industrial parks and expanding business districts, Guelph remains one of Ontario’s growing commercial leasing and investment markets.
Commercial Properties for Lease in Guelph | Commercial Real Estate Guelph
Commercial Properties for Lease in Guelph | Commercial Real Estate Guelph
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16 - 340 WOODLAWN ROAD W in Guelph (Willow West/Sugarbush/West Acres): Retail for lease : MLS®# X13769184
16 - 340 WOODLAWN ROAD W Guelph (Willow West/Sugarbush/West Acres) N1H 7K6 $14 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13769184
- Floor Area:
- 3,500 sq. ft.
Prime service commercial space in a high-traffic, highly visible plaza with convenient access to the Hanlon Expressway and Highway 401. Unit 16 offers approximately 3,500 SF of unfinished warehouse space, providing a blank canvas that can be built out to suit a variety of commercial uses. High ceilings offer the potential for a mezzanine to create additional usable space. Flexible lease terms and occupancy available, with ample plaza parking. Excellent opportunity to customize the space to meet your business needs. (id:2493) More detailsListed by Keller Williams Home Group Realty
- Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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587 HANLON CREEK Boulevard Unit# 21 in Guelph: Condo for lease : MLS®# 40862317
587 HANLON CREEK Boulevard Unit# 21 Guelph N1C 0B3 
$20 /sqftIndustrial- Status:
- For Lease
- MLS® Num:
- 40862317
- Build. Type:
- Other
- Floor Area:
- 2,248 sq. ft.
Industrial Condo Unit in Guelph, ON is For Lease. Located at the Hanlon Expressway and approximately 7 minutes from Highway 401. Features approximately 2,248 Sqft. including 1,523 Sqft. on the First Floor + 725 Sqft. on the Second Floor, with a 22' ceiling height and 10' × 10' drive-in loading bay. Lease Rate: $20/Sqft. + TMI: $7.90/Sqft. Flexible BP-3 Zoning permits a variety of uses including manufacturing, warehouse, medical office/clinic, office, commercial/cloud kitchen, beauty/hair salon, recreational, school/tuition centre, research & development and much more. (id:2493) More detailsListed by HOMELIFE MIRACLE REALTY LTD - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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17 - 340 WOODLAWN ROAD W in Guelph (Willow West/Sugarbush/West Acres): Retail for lease : MLS®# X13769116
17 - 340 WOODLAWN ROAD W Guelph (Willow West/Sugarbush/West Acres) N1H 7K6 $14 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13769116
- Floor Area:
- 2,000 sq. ft.
Prime service commercial space in a high-traffic, highly visible plaza with convenient access to the Hanlon Expressway and Highway 401. Unit 17 is currently unfinished warehouse space, providing a blank canvas that can be built out to suit a variety of commercial uses. Flexible lease terms and occupancy available, with ample plaza parking. Excellent opportunity for a tenant looking to customize a well-located Guelph commercial space to fit their specific business needs. (id:2493) More detailsListed by Keller Williams Home Group Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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9 - 340 WOODLAWN ROAD W in Guelph (Willow West/Sugarbush/West Acres): Retail for lease : MLS®# X13768984
9 - 340 WOODLAWN ROAD W Guelph (Willow West/Sugarbush/West Acres) N1H 7K6
$14 /sqftRetail- Status:
- For Lease
- MLS® Num:
- X13768984
- Floor Area:
- 2,000 sq. ft.
Prime service commercial space in a high-traffic, highly visible plaza with convenient access to the Hanlon Expressway and Highway 401. Unit 9 offers approximately 2,000 SF of flexible space suitable for a variety of commercial uses. Features include a rear man door, ample plaza parking and flexible lease terms/occupancy. No existing washroom within the unit; one may be added to suit tenant requirements. Excellent opportunity for businesses seeking an accessible and well-located Guelph commercial space. (id:2493) More detailsListed by Keller Williams Home Group Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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21 - 587 HANLON CREEK BOULEVARD in Guelph (Kortright West): Industrial for lease : MLS®# X13767902
21 - 587 HANLON CREEK BOULEVARD Guelph (Kortright West) N1C 0B3
$20 /sqftIndustrial- Status:
- For Lease
- MLS® Num:
- X13767902
- Floor Area:
- 2,248 sq. ft.
Industrial Condo Unit in Guelph, ON is For Lease. Located at the Hanlon Expressway and approximately 7 minutes from Highway 401. Features approximately 2,248 Sqft. including 1,523 Sqft. on the First Floor + 725 Sqft. on the Second Floor, with a 22' ceiling height and 10' 10' drive-in loading bay. Lease Rate: $20/Sqft. + TMI: $7.90/Sqft. Flexible BP-3 Zoning permits a variety of uses including manufacturing, warehouse, medical office/clinic, office, commercial/cloud kitchen, beauty/hair salon, recreational, school/tuition centre, research & development and much more. (id:2493) More detailsListed by HOMELIFE/MIRACLE REALTY LTD - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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100 - 21 LEWIS ROAD in Guelph (Willow West/Sugarbush/West Acres): Office for lease : MLS®# X13750856
100 - 21 LEWIS ROAD Guelph (Willow West/Sugarbush/West Acres) N1H 1E9
$15.50 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13750856
- Floor Area:
- 6,040 sq. ft.
Elevate your business at 21 Lewis Road with this fantastic office building featuring a prominent ground floor presence combined with functional lower-level office and workspace. Enjoy a prime northern Guelph location just minutes from the essential retail, dining, and highway connections along Woodlawn Road and Speedvale Avenue, with high visibility and quick access to the Hanlon Expressway.This versatile space boasts abundant on-site parking and a functional layout tailored for professional operations. The ground floor welcomes clients with a dedicated reception area, a spacious open-concept work zone, perimeter private offices, and two large washrooms. The lower level extends your operational footprint, offering additional private offices, open areas, and extra washrooms, making it ideal for a corporate head office, tech firm, professional services, or medical/health administration use. (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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78 CARDEN STREET in Guelph (Downtown): Office for lease : MLS®# X13750864
78 CARDEN STREET Guelph (Downtown) N1H 2Z7
$16 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13750864
- Bathrooms:
- 3
- Floor Area:
- 7,500 sq. ft.
This turnkey office space in downtown Guelph provides a highly functional layout featuring an open-concept work area, private offices, a kitchen/staff room, and three washrooms, including one barrier-free accessible unit. The facility is well-equipped for diverse operational requirements, offering three-phase power and a full basement with 7-foot ceilings suitable for workshop use or secure storage. Zoned D.1, the premises support a wide range of permitted uses, including professional and administrative offices, financial institutions, medical clinics, personal service shops, and cultural facilities, making this an ideal hub for large organizations or businesses seeking a versatile, high-capacity commercial environment. **** MAIN LEVEL 4500 sf at $16 , BASEMENT 3000 sf at $8 **** (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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200 - 15 LEWIS ROAD in Guelph (Willow West/Sugarbush/West Acres): Office for lease : MLS®# X13742968
200 - 15 LEWIS ROAD Guelph (Willow West/Sugarbush/West Acres) N1H 1E9
$15.50 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13742968
- Floor Area:
- 2,310 sq. ft.
Elevate your practice or corporate headquarters with a premier leasing opportunity at Unit 200, 15 Lewis Road. Strategically positioned just steps off the Hanlon Parkway in Guelph's dynamic north end, this exceptional commercial space offers the ultimate combination of high-visibility exposure and effortless regional accessibility for both clients and staff. Boasting prominent signage opportunities and ample on-site parking, the building ensures a seamless first impression from the moment visitors arrive. Spanning a generous, highly efficient footprint, the layout has been thoughtfully designed to support a wide spectrum of professional uses. Whether you are expanding a medical or wellness clinic, establishing a forward-thinking law office, housing an accounting firm, or scaling a specialized consulting practice, the configuration adapts fluidly to your operational needs. Inside, you will find an efficient arrangement featuring bright private offices, a dedicated executive boardroom for collaborative sessions, a convenient kitchenette, and private washrooms.Join a thriving, synergistic community of established professional and healthcare-adjacent services. With rapid links to Highway 7 and Highway 401, commuting from across the Tri-Cities, GTA, or local neighboruhoods is remarkably straightforward. This is a great opportunity to secure a turnkey, professional environment in the Guelph market. (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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200 - 21 LEWIS ROAD in Guelph (Willow West/Sugarbush/West Acres): Office for lease : MLS®# X13723994
200 - 21 LEWIS ROAD Guelph (Willow West/Sugarbush/West Acres) N1H 1E9
$15.50 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13723994
- Floor Area:
- 3,016 sq. ft.
Elevate your business at 21 Lewis Road with a modern second-floor suite featuring a private entrance, ample on-site parking, and high visibility ideal for signage due to its proximity to the Hanlon Expressway. The bright, updated open-concept interior maximizes usable space, surrounded by perimeter private offices, a kitchen, and washrooms. Enjoy a prime northern Guelph location just minutes from the essential retail, dining, and highway connections along Woodlawn Road and Speedvale Avenue. (id:2493) More detailsListed by Royal LePage Royal City Realty - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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106 - 649 SCOTTSDALE DRIVE in Guelph (Kortright West): Office for lease : MLS®# X13665678
106 - 649 SCOTTSDALE DRIVE Guelph (Kortright West) N1G 4T7
$18.95 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13665678
- Floor Area:
- 681 sq. ft.
Bright and inviting first-floor office space in the main building at 649 Scottsdale Drive. This cozy and efficient unit is conveniently located near the main entrance and features tall ceilings and large windows that provide an abundance of natural light. An excellent option for a professional office, service-based business, or other user seeking a well-maintained space in an established professional building. Heat, air conditioning, and electricity are included in TMI. Convenient South Guelph location with easy access to Stone Road, Highway 6, public transit, nearby amenities, and ample on-site parking. Additional units of varying sizes are also available within the building. (id:2493) More detailsListed by RE/MAX PROFESSIONALS INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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202 - 649 SCOTTSDALE DRIVE in Guelph (Kortright West): Office for lease : MLS®# X13665720
202 - 649 SCOTTSDALE DRIVE Guelph (Kortright West) N1G 4T7
$18.95 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13665720
- Floor Area:
- 1,050 sq. ft.
Well-positioned second-floor office space in the main building at 649 Scottsdale Drive. This functional and efficient unit offers a practical layout with plenty of flexibility for a variety of professional office or service-based uses. An excellent opportunity for a business looking for a well-maintained space in an established professional building, with heat, air conditioning, and electricity included in TMI. Convenient South Guelph location with easy access to Stone Road, Highway 6, public transit, nearby amenities, and ample on-site parking. Additional units of varying sizes are also available within the building. (id:2493) More detailsListed by RE/MAX PROFESSIONALS INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
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205 - 649 SCOTTSDALE DRIVE in Guelph (Kortright West): Office for lease : MLS®# X13665748
205 - 649 SCOTTSDALE DRIVE Guelph (Kortright West) N1G 4T7
$18.95 /sqftOffice- Status:
- For Lease
- MLS® Num:
- X13665748
- Floor Area:
- 5,813 sq. ft.
Exceptional corner office opportunity in the main building at 649 Scottsdale Drive. This expansive and highly versatile unit offers an abundance of natural light through extensive windows, creating a bright and welcoming professional environment. A standout feature is the walkout to a huge private terrace, providing a rare and valuable outdoor amenity for staff, clients, or meetings. Ideal for a larger professional office, medical practice, corporate user, or service-based business seeking a prominent space in an established South Guelph building. Heat, air conditioning, and electricity are included in TMI. Convenient location with easy access to Stone Road, Highway 6, public transit, nearby amenities, and ample on-site parking. Additional units of varying sizes are also available within the building. (id:2493) More detailsListed by RE/MAX PROFESSIONALS INC. - Ravneet Kaur
- Royal Star Realty Inc
- (437) 788-5550
- Contact by Email
Data was last updated September 15, 2026 at 11:15 PM (UTC)
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Guelph Commercial Leasing FAQs
What types of commercial properties are available for lease in Guelph?
Commercial leasing opportunities in Guelph may include industrial buildings, office space, retail units, warehouses, mixed-use developments, and commercial leasing properties across Southwestern Ontario.
Why do businesses lease commercial properties in Guelph?
Guelph attracts commercial tenants due to its growing population, manufacturing sector, transportation access, expanding business market, and strong commercial development across Southwestern Ontario.
Can businesses find industrial, office, and retail leasing opportunities in Guelph?
Commercial tenants can explore industrial space, office leasing opportunities, retail units, warehouses, mixed-use developments, and commercial leasing opportunities throughout Guelph and surrounding regional markets.
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