Commercial Properties for Lease in Hamilton

Explore commercial properties for lease in Hamilton including industrial buildings, warehouses, office space, retail units, mixed-use developments, and commercial leasing opportunities across Hamilton and Southwestern Ontario.

Hamilton continues attracting logistics operators, manufacturers, retailers, professional businesses, and commercial tenants searching for industrial, office, retail, and mixed-use leasing opportunities throughout the region.

From industrial districts and logistics corridors to commercial plazas, waterfront developments, and expanding business hubs, Hamilton remains one of Ontario’s strongest commercial leasing markets.

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Commercial Properties for Lease in Hamilton | Commercial Real Estate Hamilton

Commercial Properties for Lease in Hamilton | Commercial Real Estate Hamilton

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  • 612 UPPER JAMES Street Unit# Upper LVL in Hamilton: Office for lease : MLS®# 40831280

    612 UPPER JAMES Street Unit# Upper LVL Hamilton L9C 2Z1
    Main Photo: 612 UPPER JAMES Street Unit# Upper LVL in Hamilton: Office for lease : MLS®# 40831280

    612 UPPER JAMES Street Unit# Upper LVL Hamilton L9C 2Z1

    $15 /sqft
    Office
    Status:
    For Lease
    MLS® Num:
    40831280
    Floor Area:
    2,086 sq. ft.
    2,086sf walkup office unit, freshly renovated. Mixture of private offices and open space. Kitchenette. Good parking. Great central mountain location. Note $10 additional rent TMI plus utilities and HST charged. (id:2493) More details
    Listed by Martel Commercial Realty Inc.
    LISTING DETAILS

  • 612 UPPER JAMES Street Unit# Whole Bldg in Hamilton: Office for lease : MLS®# 40831243

    612 UPPER JAMES Street Unit# Whole Bldg Hamilton L9C 2Z1
    Main Photo: 612 UPPER JAMES Street Unit# Whole Bldg in Hamilton: Office for lease : MLS®# 40831243

    612 UPPER JAMES Street Unit# Whole Bldg Hamilton L9C 2Z1

    $22.50 /sqft
    Office
    Status:
    For Lease
    MLS® Num:
    40831243
    Floor Area:
    4,196 sq. ft.
    Full 2 story building for lease. Extensive recent renovations. Main floor fully configured for dental user. Upper level walkup a combination of private offices and open space with a kitchenette. Great parking and prime central mountain location. (id:2493) More details
    Listed by Martel Commercial Realty Inc.
    LISTING DETAILS

  • 612 UPPER JAMES Street Unit# Main FL in Hamilton: Office for lease : MLS®# 40831229

    612 UPPER JAMES Street Unit# Main FL Hamilton L9C 2Z1
    Main Photo: 612 UPPER JAMES Street Unit# Main FL in Hamilton: Office for lease : MLS®# 40831229

    612 UPPER JAMES Street Unit# Main FL Hamilton L9C 2Z1

    $30 /sqft
    Office
    Status:
    For Lease
    MLS® Num:
    40831229
    Floor Area:
    2,010 sq. ft.
    Wonderful turnkey dental unit with 4 treatment rooms and spacious office are in rear. Non-exclusive use of basement. Fully plumbed. Great parking and prime central mountain location. Available immediately. (id:2493) More details
    Listed by Martel Commercial Realty Inc.
    LISTING DETAILS

  • 1100 SOUTH SERVICE Road Unit# 109 in Hamilton: Condo for lease : MLS®# 40832979

    1100 SOUTH SERVICE Road Unit# 109 Hamilton L8E 0C5
    Main Photo: 1100 SOUTH SERVICE Road Unit# 109 in Hamilton: Condo for lease : MLS®# 40832979

    1100 SOUTH SERVICE Road Unit# 109 Hamilton L8E 0C5

    $13.95 /sqft
    Industrial
    Status:
    For Lease
    MLS® Num:
    40832979
    Floor Area:
    1,112 sq. ft.
    Clean industrial unit with a bonus mezzanine of approximately 750 sq. ft. Features include two drive-in doors plus a separate man door. A shared receptionist is available at the front of the unit as an added bonus to receive mail and greet guests. Office space available in needed. Conveniently located just minutes from the Fruitland Road/QEW exit, with plenty of nearby amenities including Winona Crossings, Costco, the GO Station, and more. Don’t miss this exceptional opportunity. (id:2493) More details
    Listed by RE/MAX Escarpment Realty Inc.
    LISTING DETAILS

  • 1&2 - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164616

    1&2 - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2
    Main Photo: 1&2 - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164616

    1&2 - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2

    $40 /sqft
    Retail
    Status:
    For Lease
    MLS® Num:
    X13164616
    Major Bus.:
    Retail and Wholesale
    Build. Type:
    Retail
    Floor Area:
    2,698 sq. ft.
    39 Mallard Trail is a new Plaza construction located in heart of the growing neighborhood of Waterdown South. Delivery will be in 12-18 months - so, if you act fast, there is time to request plan changes to customise to your requirements. Permitted uses include clinics (dental, physicians, phiso, pharmacy, etc. ), place of recreation, restaurant, convenience or fast food, financial institutions and more. 13 parking spots available but lots of designated on-street parking in this forward-thinking pedestrian-designed community. Place your business in the middle of Waterdowns best demographics ! TMI estimated at $10.00 psf. Tenant pays separately metered utilities. (id:2493) More details
    Listed by RE/MAX ESCARPMENT REALTY INC.
    LISTING DETAILS

  • 1 & 2 & 3 - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164528

    1 & 2 & 3 - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2
    Main Photo: 1 & 2 & 3 - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164528

    1 & 2 & 3 - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2

    $40 /sqft
    Retail
    Status:
    For Lease
    MLS® Num:
    X13164528
    Major Bus.:
    Retail and Wholesale
    Floor Area:
    4,127 sq. ft.
    39 Mallard Trail is a new Plaza construction located in heart of the growing neighborhood of Waterdown South. Delivery will be in 12-18 months - so, if you act fast, there is time to request plan changes to customise to your requirements. Permitted uses include clinics (dental, physicians, phiso, pharmacy, etc. ), place of recreation, restaurant, convenience or fast food, financial institutions and more. 13 parking spots available but lots of designated on-street parking in this forward-thinking pedestrian-designed community. Place your business in the middle of Waterdowns best demographics ! TMI estimated at $10.00 psf. Tenant pays separately metered utilities. (id:2493) More details
    Listed by RE/MAX ESCARPMENT REALTY INC.
    LISTING DETAILS

  • FULL - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164558

    FULL - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2
    Main Photo: FULL - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164558

    FULL - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2

    $38 /sqft
    Retail
    Status:
    For Lease
    MLS® Num:
    X13164558
    Major Bus.:
    Retail and Wholesale
    Build. Type:
    Retail
    Floor Area:
    5,484 sq. ft.
    39 Mallard Trail is a new Plaza construction located in heart of the growing neighborhood of Waterdown South. Delivery will be in 12-18 months - so, if you act fast, there is time to request plan changes to customise to your requirements. Permitted uses include clinics (dental, physicians, phiso, pharmacy, etc. ), place of recreation, restaurant, convenience or fast food, financial institutions and more. 13 parking spots available but lots of designated on-street parking in this forward-thinking pedestrian-designed community. Place your business in the middle of Waterdowns best demographics ! TMI estimated at $10.00 psf. Tenant pays separately metered utilities (id:2493) More details
    Listed by RE/MAX ESCARPMENT REALTY INC.
    LISTING DETAILS

  • 4 - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164588

    4 - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2
    Main Photo: 4 - 39 MALLARD TRAIL in Hamilton (Waterdown): Retail for lease : MLS®# X13164588

    4 - 39 MALLARD TRAIL Hamilton (Waterdown) L8B 1Z2

    $40 /sqft
    Retail
    Status:
    For Lease
    MLS® Num:
    X13164588
    Major Bus.:
    Retail and Wholesale
    Floor Area:
    1,358 sq. ft.
    39 Mallard Trail is a new Plaza construction located in heart of the growing neighborhood of Waterdown South. Delivery will be in 12-18 months - so, if you act fast, there is time to request plan changes to customise to your requirements. Permitted uses include clinics (dental, physicians, phiso, pharmacy, etc. ), place of recreation, restaurant, convenience or fast food, financial institutions and more. 13 parking spots available but lots of designated on-street parking in this forward-thinking pedestrian-designed community. Place your business in the middle of Waterdowns best demographics ! TMI estimated at $10.00 psf. Tenant pays separately metered utilities. (id:2493) More details
    Listed by RE/MAX ESCARPMENT REALTY INC.
    LISTING DETAILS

  • 14 DUKE Street Unit# Main in Hamilton: Office for lease : MLS®# 40820123

    14 DUKE Street Unit# Main Hamilton L8P 1X1
    Main Photo: 14 DUKE Street Unit# Main in Hamilton: Office for lease : MLS®# 40820123

    14 DUKE Street Unit# Main Hamilton L8P 1X1

    $31 /sqft
    Office
    Status:
    For Lease
    MLS® Num:
    40820123
    Floor Area:
    2,363 sq. ft.
    Turnkey medical clinic available for sublease! Existing headlease runs until August 2030. Fully equipped and ready for immediate practice. Ideal for medical or paramedical users such as RMT, physio, dentist, or cosmetic surgery. Includes surgery-approved suite (formerly operated by plastic surgeon), available for recertification for clinical use. Complete medical equipment includes exam tables, instrument trays, suture kits, bandages, chairs and more. Walk in Monday, see patients Monday! Physical elements of the complex include wheelchair ramp for accessible ground floor entry and 12 on-site parking spaces downtown – a rarity in Hamilton’s medical corridor. Being 450 metres from St. Joseph’s Hospital, 220 metres from Hamilton GO Station, 440 metres from Hamilton City Hall, and 400 metres from the core of the city's King and James intersections, the property is immediately accessible to and from many of Hamilton's major nexus points of healthcare, commerce, and civic government. With the property's ample parking, downtown walkability, and proximity to numerous transit stops and Frank Cooke Transit Terminal, the property is immediately accessible for all users, whether pedestrians, drivers, or transit-riders. Fully equipped with Fibre optic, backup generator, full security system, video surveillance ready for a new user. Note purchase opportunity also available for entire building with established income streams. (id:2493) More details
    Listed by Corcoran Horizon Realty
    LISTING DETAILS

  • 14 DUKE Street Unit# Main in Hamilton: Retail for lease : MLS®# 40830002

    14 DUKE Street Unit# Main Hamilton L8P 1X1
    Main Photo: 14 DUKE Street Unit# Main in Hamilton: Retail for lease : MLS®# 40830002

    14 DUKE Street Unit# Main Hamilton L8P 1X1

    $31 /sqft
    Retail
    Status:
    For Lease
    MLS® Num:
    40830002
    Floor Area:
    2,363 sq. ft.
    Turnkey medical clinic available for sublease! Existing headlease runs until August 2030. Fully equipped and ready for immediate practice. Ideal for medical or paramedical users such as RMT, physio, dentist, or cosmetic surgery. Includes surgery-approved suite (formerly operated by plastic surgeon), available for recertification for clinical use. Complete medical equipment includes exam tables, instrument trays, suture kits, bandages, chairs and more. Walk in Monday, see patients Monday! Physical elements of the complex include wheelchair ramp for accessible ground floor entry and 12 on-site parking spaces downtown – a rarity in Hamilton’s medical corridor. Being 450 metres from St. Joseph’s Hospital, 220 metres from Hamilton GO Station, 440 metres from Hamilton City Hall, and 400 metres from the core of the city's King and James intersections, the property is immediately accessible to and from many of Hamilton's major nexus points of healthcare, commerce, and civic government. With the property's ample parking, downtown walkability, and proximity to numerous transit stops and Frank Cooke Transit Terminal, the property is immediately accessible for all users, whether pedestrians, drivers, or transit-riders. Fully equipped with Fibre optic, backup generator, full security system, video surveillance ready for a new user. Note purchase opportunity also available for entire building with established income streams. (id:2493) More details
    Listed by Corcoran Horizon Realty
    LISTING DETAILS

  • 108 - 64 HATT STREET in Hamilton (Dundas): Office for lease : MLS®# X13121154

    108 - 64 HATT STREET Hamilton (Dundas) L9H 7T6
    Main Photo: 108 - 64 HATT STREET in Hamilton (Dundas): Office for lease : MLS®# X13121154

    108 - 64 HATT STREET Hamilton (Dundas) L9H 7T6

    $13 /sqft
    Office
    Status:
    For Lease
    MLS® Num:
    X13121154
    Floor Area:
    1,377 sq. ft.
    Functional storage space available within a converted Dundas landmark building, ideal for inventory overflow, contractor storage, equipment, archives, or general business support use. Convenient access to shared loading areas and ample on-site parking for staff and users. Centrally located in Dundas with quick access to Hamilton and surrounding areas. C5 zoning permits a wide range of commercial uses including office, studio, retail, service-based businesses, and light industrial uses (id:2493) More details
    Listed by Sotheby's International Realty Canada, Brokerage
    LISTING DETAILS

  • 14 DUKE STREET in Hamilton (Durand): Office for lease : MLS®# X13122802

    14 DUKE STREET Hamilton (Durand) L8P 1X1
    Main Photo: 14 DUKE STREET in Hamilton (Durand): Office for lease : MLS®# X13122802

    14 DUKE STREET Hamilton (Durand) L8P 1X1

    $31 /sqft
    Office
    Status:
    For Lease
    MLS® Num:
    X13122802
    Floor Area:
    2,363 sq. ft.
    Turnkey medical clinic available for sublease! Existing headlease runs until August 2030. Fully equipped and ready for immediate practice. Ideal for medical or paramedical users such as RMT, physio, dentist, or cosmetic surgery. Includes surgery-approved suite (formerly operated by plastic surgeon), available for recertification for clinical use. Complete medical equipment includes exam tables, instrument trays, suture kits, bandages, chairs and more. Walk in Monday, see patients Monday! Physical elements of the complex include wheelchair ramp for accessible ground floor entry and 12 on-site parking spaces downtown - a rarity in Hamilton's medical corridor. Being 450 metres from St. Joseph's Hospital, 220 metres from Hamilton GO Station, 440 metres from Hamilton City Hall, and 400 metres from the core of the city's King and James intersections, the property is immediately accessible to and from many of Hamilton's major nexus points of healthcare, commerce, and civic government. With the property's ample parking, downtown walkability, and proximity to numerous transit stops and Frank Cooke Transit Terminal, the property is immediately accessible for all users, whether pedestrians, drivers, or transit-riders. Fully equipped with Fibre optic, backup generator, full security system, video surveillance ready for a new user. Note purchase opportunity also available for entire building with established income streams. (id:2493) More details
    Listed by Corcoran Horizon Realty
    LISTING DETAILS
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Data was last updated May 29, 2026 at 06:15 PM (UTC)

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Hamilton Commercial Leasing FAQs

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